[BlackSoy]

Hi everyone! First time poster

I am currently on HRT (Estradiol monotherapy) + Dutasteride. I’m looking to maximize my breast growth potential (and overall fat redistribution). I’ve done quite a bit of research on Breast Nexum, specifically diving into Lotus's "Project X," but I still have some specific questions.

I’m aware that adding phytoestrogens to an injectable Estradiol regimen is generally counterproductive, as the weaker phytos might compete with the bioidentical E for receptor sites. I plan to avoid them.

I’m very interested in adding a pro-aromatase, which seems logical given the Dutasteride in my system. However, finding reliable sources is tough. White Peony Root is the gold standard but it’s extremely difficult for me to source where I live.

Forskolin: I’ve heard it induces aromatase expression, but I’ve also read it can simultaneously increase testosterone. Could borage oil be a viable alternative? 

Does anyone have suggestions for other reliable aromatase inducers?

I’m curious about natural anti-androgens. I’ve read some mentions of Lemon (specifically lemon water) potentially blocking the CYP17 enzyme to suppress T levels. Is there any truth to this or did I misunderstand the mechanism?

Are there other effective ways to lower T levels naturally (without increase SHBG levels)? I know having a small amount of T is beneficial for growth, but I want to ensure it’s properly managed.

Aside from the above, I want definitely to integrate:

Vitamin D3

MSM

Amino Acids

I would love to hear from anyone who has successfully combined pharmaceutical HRT with these specific NBE principles. Thank you!

[jo dolphine]

Borage oil is more of an anti-inflammatory / fatty acid supplement than a known aromatase inducer. I don't think it's a substitute for white peony.

Lemon / lemon water as a meaningful CYP17 blocker is not something I've ever come across. I'm struggling to see this as likely to be true.

I've heard a lot about spearmint. Is that something you've looked at?

[Heaven's Night]

Look up topical cream protocol thread. Learn about amino acids, L-tyrosine, Acetyl L-carnitine, L-ornithine and L-arginine in particular. Read about vitamin D3, MSM and calcium citrate as a combination. Read about bovine glandulars. Physical stimulation is hugely beneficial, massage, lactation pump, nipple correctors such as Supple Nips. Both passive and active stimulation help to boost blood circulation and growth signaling.

[BlackSoy]

Borage oil is more of an anti-inflammatory / fatty acid supplement than a known aromatase inducer. I don't think it's a substitute for white peony.

Lemon / lemon water as a meaningful CYP17 blocker is not something I've ever come across. I'm struggling to see this as likely to be true.

I've heard a lot about spearmint. Is that something you've looked at?

Thanks for the feedback! I think you're right. I probably got confused because I saw Borage Oil and EPO mentioned as aromatase inducers in Project X (around page 349), but they might not be as potent or effective as white peony. (I’m not an expert on the science side of things yet, and English isn’t my first language lol).

Regarding the lemon water, I think Lotus mentions it (and other fruits/veggies) as potential CYP17 blockers on pages 331 and 391, but as you suggested, the potency is likely the main issue there.

Spearmint seems like an easy addition since its anti-androgenic effects are better documented. Thanks for the tip! By the way, do you happen to know if spearmint can cause SHBG to increase too much?

[BlackSoy]

Look up topical cream protocol thread. Learn about amino acids, L-tyrosine, Acetyl L-carnitine, L-ornithine and L-arginine in particular. Read about vitamin D3, MSM and calcium citrate as a combination. Read about bovine glandulars. Physical stimulation is hugely beneficial, massage, lactation pump, nipple correctors such as Supple Nips. Both passive and active stimulation help to boost blood circulation and growth signaling.

Omg, thank you so much for these suggestions!
I’ve already looked into the posts regarding amino acids and their benefits for breast growth, but I will definitely dive deeper now!

Also, Vitamin D3 and MSM are additions that I absolutely want to include. I’ve read that they provide so many benefits and stimulate tissue growth, repair, IGF-1, and so on.

One question: do you think the topical cream protocol is good for someone in their early months of HRT? Or should I maybe skip the progesterone part of the protocol for now?

Thank you for helping me! I’m going to look up everything you mentioned.

[Heaven's Night]

MSM + D3 + Calcium citrate is very useful. Its one of the few things I've been on for more than five years almost without interruption, its effects on growing boobs I would say are undeniable, but its subtle, one of the hormonal side shows that help everything else do its thing. The entire HGH, IGF-1, HGF approach is worth digging into. Anything that deals with growth hormone and growth factor hacks obviously comes with its risks but these are a big big factor on growing everything, in cluding boobs. 

Don't skip prog, the TCP is very likely to be one of the best bets on enhancing your HRT. Also one of the benefits is that you're not going to dramatically shift your over all hormone balance as the effect is largely localised. I haven't noticed any significant changes in my over all mood and health and so on but a world of difference on breast growth.

In few months I'll have been on it for three years and I'm planning on stopping for now as I'm reaching goals and need to save money for others things such as long term HRT supply. I'm going to do a big post mortem update on the whole thing. There's still some things to be tested out which I haven't been able yet so in the future I might do another go at it.

About progesterone, I'm at the school of thought to go on it as early as possible and not shying away from it regardless of in which development stage you're in. It doesn't seem to stall anything, or slow down anything or cause any hindrance, rather the opposite. This is all about the ideas of approach onto it, some think its better to delay and others start right away when possible and there doesn't seem to be any conclusive evidence for or against because extensive study is missing. But lived experience seems to imply strongly, that early progesterone use is beneficial.

And as part of the TCP I think it is essential. DHEA and progesterone form the core of it, additional estradiol seems to help, low contentrated DMSO cream is highly beneficial for absorbtion, doesn't seem to cause any nasty side effects. There's a lot more talk about this subject in the TCP thread itself and I've posted a lot in my main thread too. Lotus mostly posted her findings in the TCP thread. (You can find both from going to my profile and clicking on show threads.)