[Heaven's Night]

Thank you. How am I not surprised of your first comment since I've been picking up ideas from your thread on the way. 

Hi Didi,

I'm not sure of your meaning (How am I not surprised of your first comment). My meaning comes from me thinking I can't really tweak my core NBE supplements that works for me because it's a Lotus program. See, I can suggest adding vitamin C with the MSM because the former helps synthesize collagen. Interesting that the metabolism of MSM uses the Jak2/STAT5b signaling pathway which indeed involves aromatase (which is the CYP19 enzyme). In other words it helps turn T (testosterone) to estradiol (E2.

That's very interesting that the creams will work together, that was something I was going to ask more about but you just pre emptied the need.  

Pueraria mirifica is structurally similar to E2 (estradiol), whereas estradiol and estriol (E3) are bioidentical to estrogen receptors. Phytoestrogens in general are anti-estrogen by occupying receptor cells which is good for stopping cancer.
 
 

So far I haven't found Reishi being sold on the shops I frequent, but I need to look into it.

 

I was going to ask what anti-androgen you're taking?. Progesterone inhibits DHT, it specifically inhibits DHT in the MEC-mammary epithelial cells- which reside inside the ductal tree known as alveoli (lobes). Essentially, androgens are anti-estrogen for breast growth. 

Thanks for magnificent advice, I will definitely tweak my program for a bit.

Your welcome. Feel free to ask questions

What I mean was that I've picked the ideas mainly from your thread. MSM helps with aromatase? That's cool, I had no idea of that or I missed it before. Very nice. I'm not taking any specific anti androgen as I've been yet undecided on which one to try as there seems to be many. WP and reishi have been highest on 'my list' to try out, but I haven't found where to buy them... But since your advice is to get reishi, I would guess that's the one to go for. I need to do a search to see where to get it.

So far, so good. It appears that PC is doing its thing, I haven't got the "pm high" about one hour after taking it in the last days when I've been on progestrone too which is kinda nice. I've felt more stable, less emotional. Excluding last night as I was tired as hell and had a bit of sleep deprivation going on. I'm on the day 6 of the current cycle now. Breast buds feel a bit swollen and sore once again. So far its going exactly like I expected, boobies will likely to swell a lot and peak in about two weeks again. I'm very interested in seeing how will progestrone change my moods when I keep going for longer, I have got clear symptoms of too high E levels if I don't take complete break in time, but PC is supposed to keep it in check somewhat. (I'm also on lower PM dose than before.)

Again, thanks Lotus for the information, there's always some new cool detail there to know.