[Menina]

Hi, I am on therapy for 4 months, using transdermal bioidentical estradiol 1.5 - 2.0 mg, and spironolactone 50 mg to have a female body with good results, but there's something that bothers me. When I get aroused, my penis starts to grow and it hurts quite a bit. It's not a sharp pain, it's like I feel it growing beyond its limit, even though it's only halfway there. Besides the pain, it doesn't get as hard as it used to, which is to be expected. I also have difficulty reaching orgasm when masturbating, whether thinking about men or women (I like both). I know my erogenous zones are changing to a female pattern, but I'd like to preserve the male ones as well. I think bicalutamide doesn't destroy male functions because it at least preserves testosterone at its normal level. What do you think about this? How should I transition? What dosage of bicalutamide should I use?

[Menina]

Hello everyone, today is the tenth day of transitioning from spironolactone to bicalutamide. I've been feeling good, it seems like I'm more focused on my feminine state, as if I've never had a male body before. However, I've noticed a side effect, perhaps an adaptation issue: I've been having mild diarrhea, meaning sometimes my bowels rumble a lot and when I defecate, liquid comes out with the stool, but nothing excessive. I think this will pass with time.

[flamesabers]

Hello Menina,

IIRC, bicalutamide doesn't block testosterone production, but rather it blocks the body's intake of it. I've never been on this particular medication for my transition (I asked my doctor about this a while ago, but he suggested Eligard would be more suitable, as bloodwork measuring testosterone levels would be more informational with Eligard than bicalutamide).